Endocrine Abstracts

Endokinin B (EKB) is a recently identified tachykinin whose role is not yet fully understood. EKB displays equivalent affinity for the three tachykinin receptors as substance P (SP) which it is often found co-expressed with. SP has been implicated in a variety of neuroendocrinological responses including stress regulation, and affective and anxiety-related behaviours. An important aspect, therefore, is to dissect a distinct role for EKB from that of SP. Here, we have attempted...